Posts tagged with: AI in healthcare

Journal Safari: AlphaGenome Knows Which Way, Not How Much

Published on October 14, 2026 9 min read

Journal Safari #7. DeepMind's AlphaGenome reads a megabase of DNA, predicts thousands of genomic tracks, and matches or beats the strongest competing model on 25 of 26 variant tests, mostly by a little. It calls the direction of a variant's effect far better than the size, which makes it a scanner rather than a verdict, and a decent preview of where AI in biology is right now.

Journal Safari: Ask Eleven Models, Keep the Worst Answer

Published on August 19, 2026 18 min read

Journal Safari #4. Eleven ESM protein language models were supposed to be near-interchangeable. They have different blind spots that do not overlap, and training each one on the others' best guesses puts sequence-only at the top of the ClinVar board. The gain comes off about 200 proteins, which is the part I keep chewing on.

Journal Safari Bioinformatics AI in healthcare